Learn about Pre-Alcohol
We start with a natural probiotic bacteria you already eat every day, called Bacillus subtilis. We then used a process naturally honed by bacteria to insert the instructions for making ALDH into the bacteria’s genome...
Show up for life fully
Pre-Alcohol is designed to break down an unwanted byproduct of alcohol. Drink responsibly, for an easier tomorrow.
How it works
For best results, make Pre-Alcohol your first drink of the night.
Whether it’s a glass of wine with dinner or going out with friends, pace yourself, hydrate, and get a good night’s sleep.
Seize your next day—hit the gym, get outside, play with the kids—make the most of it.
Allergen information
The Science
The world’s first genetically engineered probiotics: purpose-built to improve daily life.
Learn about Pre-Alcohol
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Your first drink of the night
It's not magic, it's science
When we drink, our bodies break down alcohol into an unwanted byproduct called acetaldehyde.
That byproduct is largely responsible for how we feel the day after drinking.
Acetaldehyde forms in two places: the liver and the gut. The liver produces an enzyme that removes it quickly. But the gut does not. So acetaldehyde builds up and lingers, filtering out into the rest of our body over time.
Pre-Alcohol helps our gut catch up by temporarily adding a probiotic that can break down acetaldehyde. This probiotic – Bacillus subtilis ZB183™ – has been engineered to produce the same type of enzyme as our liver: one that digests acetaldehyde.
Leveraging cutting-edge biotechnology, we've engineered natural solutions that work in harmony with your body's chemistry.
ZBiotics Pre-Alcohol Probiotic Drink is a genetically engineered probiotic designed to break down acetaldehyde, an unwanted byproduct of alcohol. We built Pre-Alcohol for people who care about their mornings.
✓ Millions of bottles sold
✓ #1 in category on Amazon
✓ Built with biotechnology
Other products are different mixes of the same 5+ off-the-shelf vitamins and plant extracts.
We took a different approach. Using biotechnology, we identified a major unwanted byproduct of drinking alcohol—acetaldehyde—and engineered a probiotic to break it down the same way your liver does.
World's first genetically engineered probiotic
- Trusted by customers
- GRAS & FDA safety compliant
- Responsibly engineered
- Transparently labeled
Modern genetic engineering, done responsibly
Innovation should be responsible, transparent, and
trustworthy. That’s why we spent years developing the
world’s first genetically engineered probiotic with
rigorous testing and scientific integrity. Since
launching in 2019, we’ve earned the confidence of
thousands by delivering real, research-backed results.